GAIA V2 Peptide Labelling Fluidic Processor
The GAIA V2 is the next generation in peptide labeling, designed for radiometal-based labeling such as 68Ga (Gallium), 90Y (Yttrium), and 177Lu (Lutetium). With its compact and efficient design, GAIA V2 streamlines the labeling process, reducing both the space needed in the lab and overall costs. Its user-friendly interface and intuitive handling make it ideal for researchers working in radiopharmaceutical development, particularly for applications such as DOTA-TOC and PSMA.
Key Advantages
• Compact Design: GAIA V2 fits seamlessly into tight laboratory spaces, reducing the need for extensive room in hot cells.
• Cost-Effective: Reduces per-dose costs through minimized synthesis time, reduced decay, and no requirement for gases.
• Efficient Handling: Easy-to-use interface and single-use materials simplify the labeling process and minimize maintenance efforts.
• Versatile Compatibility: Can be connected to various generators including Gallileo, E&Z, ITG, and ITB Ithemba. Contact technical support for other generator models.
• Quick and Easy Synthesis: Pre-installed methods allow fast production, while the touch-controlled user interface ensures intuitive operation.
Main Features
• Radioactive Peptide Labeling: Efficient labeling with 68Ga, 90Y, 177Lu, and more.
• Single-Use Kits: All components in contact with reagents are disposable, reducing cross-contamination risk and fulfilling GMP standards.
• Automated Self-Testing: The system performs automated checks for reactor temperature, radio-detectors, valve gears, and pump function before each synthesis run.
• Quick Synthesis Control: Includes features like multiple radio detectors to enhance labeling processes, reduce yield loss, and improve quality control.
• Interactive Process Layout: Graphical editor for process layout and timetable, offering full control over synthesis with visual flow paths and method editing.
• GMP-Compliant: The GAIA V2 is designed for routine use in GMP production environments, with features such as audit trails, bar code readers, and write-protected data files.
Performance Specifications
• Power Requirements: 230V / 100VA
• Dimensions: 379 mm (L) x 195 mm (W) x 307 mm (H); Length with inlet/outlet: 440 mm
• Weight: Max 25 kg
• Operation Conditions: Temperature range: 10–40°C, max humidity: 70% RH
• Over-Pressure Stability: 5 bar
Components
• Peristaltic Pump: Speed range +/- 1 to +/- 300 rpm, with lid and rotation sensors.
• Number of Valves: 3 x 5 valves for enhanced fluidic control.
• Number of Reactors: 1 reactor for efficient synthesis control.
• Radioactivity Detectors: 3 detectors for process control, and 1 detector for fractionation.
• Sensors: Includes gas pressure sensors (200 to 7000 mbar, accuracy +/- 10 mbar) and pressure sensors.
Heating and Cooling
• Dynamic Temperature Range: 10°C to 150°C
• Heating Speed: 25°C to 100°C in less than 50 seconds
• Cooling Speed: 100°C to 30°C in less than 7 seconds
• Temperature Accuracy: +/- 1.0°C
User-Friendly Operation
The GAIA V2’s user interface is designed to be straightforward, with a touch-screen display for process monitoring. Pre-installed labeling methods allow users to run processes immediately after installation with minimal training. Additionally, GAIA V2 features color-coded connections, bar code readers, and automated error detection for hassle-free operation.
• Self-Testing Features: The system performs automated tests on key functions, ensuring operational reliability.
• Interactive Tutorials: Step-by-step video tutorials guide users through each process, increasing confidence and ease of use.
Maintenance and Service
GAIA V2 is built for long-term reliability, with minimal moving parts to reduce wear and tear. Additionally, essential components like the pump and valves can be easily exchanged, reducing downtime. Comprehensive service and warranty contracts are available, including IQ/OQ validation services performed by certified Elysia-Raytest engineers.
GMP Production and Compliance
GAIA V2 is fully compliant for use in GMP production environments. The system offers advanced features such as:
• User Access Control: For secure operation.
• Audit Trails: Ensures all operations are logged and compliant with regulatory requirements.
• Data Integrity: Write-protected files and traceable batch numbers provide complete accountability.
