GABI Nova
Introducing the GABI Nova—a cutting-edge radio flow monitor designed for radio flow measurements in nuclear medicine, SPECT, and PET laboratories. This versatile system is engineered to deliver top-notch performance for various activities and isotopes, ensuring precise and reliable detection.
Key Features:
- Wide Range of Probes & Flow Cells: Supports multiple detector probes and flow cells, allowing optimal configuration for all activities and isotopes, ensuring the best signal-to-noise ratio.
- Customizable Housing Options: Choose from three different housings—standard, Agilent-compatible, and Shimadzu-compatible—designed for seamless integration with your existing radio-HPLC system.
- Elysia Communication Protocol (ECP): Automatically recognizes detector types and serial numbers for accurate documentation and compliance with GXP standards.
- Software Integration: Fully compatible with Elysia’s Gina software and Clarity software for complete system control, digital signal transfer, data storage, and HPLC management. The GABI Nova can also integrate into existing radio-HPLC systems with third-party software solutions.
- Built for Efficiency: Adjust detector technology, scintillator, cell volume, and shielding for optimal performance across different isotopes and activities, ensuring unmatched detection capabilities.
With the GABI Nova, your lab will achieve greater efficiency, versatility, and precision in radio flow measurements, all while adhering to GMP/GLP standards. Perfect for nuclear medicine and radiopharmaceutical quality control.
MIRA Star
Introducing the MIRA Star—a high-sensitivity μ-HPLC radioactivity flow detector, specifically designed for low-flow μ-HPLC applications. Traditional radioactivity detectors struggle with small flow cells, but MIRA Star overcomes these challenges with its advanced detection technology, ensuring exceptional sensitivity for even the smallest radioactive fractions.
Key Features:
- Optimized for μ-HPLC: Designed for applications with very low eluate flow rates, MIRA Star uses ultra-small flow cells with minimal dead volume, making it perfect for precise measurements.
- Advanced Coincidence Detection: Equipped with four small, low-noise photomultipliers arranged in coincidence. This configuration ensures that even the smallest radioactive events are detected with high sensitivity.
- Multiple Detectors: Four coincidence flow detectors operate in sequence, each counting over optimal time intervals. Their combined data dramatically improves overall detection sensitivity.
- Real-Time Monitoring: The four radio-chromatograms are digitally recorded and displayed on a connected PC. By compensating for flow delays and adding the chromatograms, MIRA Star reveals radioactive fractions that would otherwise go undetected.
- Scintillator Options: Available with either internal solid scintillators or liquid scintillator admixture, providing flexibility for different applications.
The MIRA Star is the ideal solution for μ-HPLC applications, where precise, sensitive radioactivity detection is critical, offering unmatched performance in challenging low-flow scenarios.
Introducing the POMO Nova—the latest addition to our radio-flow detector family, specifically designed for beta+ and beta- emitters. The POMO Nova is the detector of choice for quality control in radiopharmacy, especially for PET tracer studies.
Key Features:
- High Sensitivity: Optimized for detecting beta+ and beta- particles, ensuring precise results in PET isotope studies.
- Low Gamma Response: Advanced flow cells with high positron efficiency and low gamma response, providing clear detection with minimal background noise.
- Ideal for PET Tracers: Tailored for the quality control of PET tracers, delivering accurate and reliable performance for QC applications.
- Seamless Integration: Built for easy integration into your Radio-HPLC chain, ensuring a smooth workflow in radiopharmaceutical laboratories.
With POMO Nova, you gain unparalleled sensitivity and detection capabilities, making it the perfect tool for PET tracer quality control and radiopharmacy applications.
Prep Probe
Introducing the Prep Probe in combination with the GABI Nova—a groundbreaking solution for semi- and preparative HPLC applications in radiopharmaceutical synthesis. This innovative system addresses the challenges of radio-detection, ensuring high sensitivity and performance in demanding environments.
Key Features:
- Enhanced Detection Capabilities: Designed for high activity levels, the Prep Probe provides reliable detection in environments where traditional detectors struggle due to extreme count rates and radiation exposure.
- Compact Design: The probe’s small size (comparable to an AA battery) allows for minimal shielding requirements, typically just 10 cm in diameter and 14 cm in height with a lead cover, making it ideal for use in hot cells where space is limited.
- Customizable HPLC Loops: Standard loop sizes of 2, 7, and 16 μl are available, with the option to create custom loops up to 1 ml, optimizing peak detectability and shape. The loop’s internal and outer diameters are adjustable to accommodate HPLC flow rates from 1 to 250 ml/min.
- Automated Peak Collection: An optional downstream 6-position valve can be controlled via software or manually, allowing for the collection of peaks of interest based on chromatogram data or defined signal thresholds.
- Flexible Installation: The probes can be used in a hot cell, combined with an HPLC system, or integrated into a synthesis unit, providing versatile options for radiopharmaceutical applications.
- Advanced Communication Protocol: The GABI Nova introduces the Elysia Communication Protocol (ECP), which enables seamless recognition of different probes and detectors, enhancing documentation and GxP compliance.
- Remote Diagnostics and Control: The ECP allows for advanced control and diagnostics of probes, ensuring optimal performance and the ability to perform remote diagnostics.
With the Prep Probe and GABI Nova, you can achieve unparalleled performance and reliability in semi- and preparative HPLC applications, ensuring the highest standards in radiopharmaceutical synthesis.
RAMONA HPLC LS Pump
Introducing the RAMONA HPLC-LS Pump*—the ideal solution for continuous admixture of liquid scintillator into radioactive labeled eluates in HPLC systems. Designed for precision and reliability, this pump is essential for laboratories engaged in radiochemical analysis.
Key Features:
- Robust Construction: The RAMONA* pump features a durable stainless steel body or an alternative peak material construction, ensuring longevity and resistance to corrosion.
- Precision Piston Design: The piston, crafted from high-quality sapphire, provides exceptional anticorrosive properties and precision for accurate flow control.
- Wear-Resistant Valves: Inlet and outlet valves made of Rubin withstand the abrasiveness of various liquid scintillator cocktails, minimizing wear and tear.
- Adjustable Flow Rate: Flow rates can be adjusted manually or controlled remotely via the GINA* software, allowing for flexibility in application. Two flow ranges are available:
- Standard Applications: 2 – 10 ml/min
- μ-Flow Rates: 0.1 – 2 ml/min
- Pulsation Compensation: The piston pump generates minimal pulsation, which is effectively compensated for in the admixture T-piece and mixture coil, ensuring smooth and consistent flow.
- High Pressure Capability: Designed to deliver high pressure, the RAMONA* pump can easily admix various scintillator cocktails into all feasible eluate compositions.
The RAMONA HPLC-LS Pump* is the perfect companion for your HPLC system, providing reliable liquid scintillator admixture for enhanced efficiency and accuracy in radiochemical applications.
RAMONA Quattro
Introducing the RAMONA Quattro*—an ultra-sensitive β-HPLC flow detector designed for unparalleled performance in radiochemical analysis. This advanced instrument integrates four beta-radioactivity coincidence flow detectors into a single, efficient unit, providing superior detection capabilities for precise chromatographic measurements.
Key Features:
- Four-Detector System: The RAMONA* Quattro employs four pairs of 2 x 1 1/8” photomultipliers arranged in coincidence, allowing for the measurement of beta radioactivity across four flow cells positioned sequentially.
- Individual Trace Monitoring: Each coincidence detector measures beta radioactivity in the HPLC flow independently, enabling detailed monitoring of individual traces. The recording PC displays all four traces simultaneously, showing the same chromatogram with slight delays as the fraction moves through each detector.
- Adjustable Flow Delays: The flow time between detectors can be determined and adjusted individually, allowing for precise alignment and analysis. This enables the generation of four simultaneous chromatograms, which can be combined into a fifth trace displaying the total count.
- Enhanced Sensitivity: By integrating peak detection during measurement, the RAMONA* Quattro significantly improves sensitivity. As peaks grow linearly by a factor of four, the background noise increases only by a factor of two, enhancing the signal-to-noise ratio.
- Flexible Display Options: Users can choose to display the four individual traces or suppress them to show only the summed result, providing versatility in data presentation.
The RAMONA Quattro* is the ideal choice for laboratories requiring high sensitivity and precision in β-HPLC flow detection, offering cutting-edge technology for advanced radiochemical applications.
RAMONA Star
Introducing the RAMONA Star—an advanced coincidence HPLC flow monitor that continues a legacy of excellence with over 2000 units installed since 1983. This state-of-the-art radioactivity-HPLC flow detector is engineered for maximum sensitivity and minimal background noise, making it an ideal choice for detecting low-energy beta minus nuclides, such as H-3.
Key Features:
- High Sensitivity Detection: Utilizes 2” diameter photomultipliers, offering superior sensitivity for liquid scintillation admixture, recognized as the most effective method for low-energy beta detection.
- Versatile Scintillator Options:
- Liquid Scintillator Admixtures: Deliver exceptional sensitivity for H-3 detection.
- Solid Scintillators: Alternative internal solid scintillator materials and particle sizes are available, providing similar efficiency for C-14 and other low-energy beta applications. The potential contamination of solid scintillators is meticulously analyzed and mitigated.
- External Scintillators: Recommended for high-energy beta applications, expanding the versatility of the RAMONA Star.
- Advanced Identification Technology: Elysia-raytest has developed a unique identification system for each flow cell, allowing for the automatic adaptation of coincidence timing based on the scintillator material used. This feature is essential for GLP compliance.
- Precision Counting and Pulse Summation: Features two identical, simultaneous counting channels, each equipped with individual lower and upper discriminators for tailored applications and calibrations. The integrated microprocessor counts single events in each channel with high accuracy.
- Real-Time Data Transfer: The count data per interval time is seamlessly transmitted to a PC running Elysia-raytest’s GINA X software, ensuring efficient data management and analysis.
- Digital Integration: Offers digital integration of regions of interest (ROI) and peaks, with statistical accuracy and limit of detection calculated, displayed, and documented for comprehensive reporting.
The RAMONA Star is the perfect solution for laboratories seeking precision, sensitivity, and reliability in beta radioactivity detection, setting a high standard for HPLC flow monitoring in radiochemical applications.